γ-Oryzanol Enhances Adipocyte Differentiation and Glucose Uptake

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γ-Oryzanol Enhances Adipocyte Differentiation and Glucose Uptake

Recent studies show that brown rice improves glucose intolerance and potentially the risk of diabetes, although the underlying molecular mechanisms remain unclear. One of the phytochemicals found in high concentration in brown rice is γ-oryzanol (Orz), a group of ferulic acid esters of phytosterols and triterpene alcohols. Here, we found that Orz stimulated differentiation of 3T3-L1 preadipocyt...

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γ-oryzanol (Orz), a steryl ferulate extracted from rice bran layer, exerts a wide spectrum of biological activities. In addition to its antioxidant activity, Orz is often associated with cholesterol-lowering, anti-inflammatory, anti-cancer and anti-diabetic effects. In recent years, the usefulness of Orz has been studied for the treatment of metabolic diseases, as it acts to ameliorate insulin ...

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ژورنال

عنوان ژورنال: Nutrients

سال: 2015

ISSN: 2072-6643

DOI: 10.3390/nu7064851